2021-


Sakreida K, Chiu WH, Dukart J, Eickhoff SB, Frodl T, Gaser C, Landgrebe M, Langguth B, Mirlach D, Rautu IS, Wittmann M, Poeppl TB.
Disentangling dyskinesia from parkinsonism in motor structures of patients with schizophrenia.
Brain Commun. 2022;4(4):fcac190. PDF

Jawinski P, Markett S, Drewelies J, Düzel S, Demuth I, Steinhagen-Thiessen E, Wagner GG, Gerstorf D, Lindenberger U, Gaser C, Kühn S.
Linking Brain Age Gap to Mental and Physical Health in the Berlin Aging Study II.
Front. Aging Neurosci. 14:791222. PDF

Gaser C, Dahnke R, Thompson PM, Kurth F, Luders E.
CAT – A Computational Anatomy Toolbox for the Analysis of Structural MRI Data.
BioRxiv, in press. PDF

Luders E, Dahnke R, Gaser C.
To smooth or not to smooth: One step closer to single-voxel accuracy without spatial smoothing.
BioRxiv, in press. PDF

Ruiz-Rizzo AL, Bublak P, Kluckow S, Finke K, Gaser C, Schwab M, Güllmar D, Müller HJ, Witte OW, Rupprecht S.
Neural distinctiveness of fatigue and low sleep quality in multiple sclerosis.
Eur J Neurol., in press. PDF

Giannakopoulos P, Montandon ML, Herrmann FR, Hedderich D, Gaser C, Kellner E, Rodriguez C, Haller S.
Alzheimer resemblance atrophy index, BrainAGE, and normal pressure hydrocephalus score in the prediction of subtle cognitive decline: added value compared to existing MR imaging markers.
Eur Radiol., in press. PDF

Ligges C, Ligges M, Gaser C.
Cross-Sectional Investigation of Brain Volume in Dyslexia.
Front Neurol. 2022;13:847919.PMID: 35350399; PMCID: PMC8957969. PDF

Rubbert C, Wolf L, Turowski B, Hedderich DM, Gaser C, Dahnke R, Caspers J; Alzheimer’s Disease Neuroimaging Initiative.
Impact of defacing on automated brain atrophy estimation.
Insights Imaging. 2022;13(1):54. PDF

Kurth F, Gaser C, Sánchez FJ, Luders E.
Brain Sex in Transgender Women Is Shifted towards Gender Identity.
J Clin Med. 2022;11(6):1582. PDF

Schmitz-Koep B, Menegaux A, Gaser C, Brandes E, Schinz D, Thalhammer M, Daamen M, Boecker H, Zimmer C, Priller J, Wolke D, Bartmann P, Sorg C, Hedderich DM.
Altered Gray Matter Cortical and Subcortical T1-Weighted/T2-Weighted Ratio in Premature-Born Adults.
Biol Psychiatry Cogn Neurosci Neuroimaging. 2022:S2451-9022(22)00052-0. PDF

Hahn T, Ernsting J, Winter NR, Holstein V, Leenings R, Beisemann M, Fisch L, Sarink K, Emden D, Opel N, Redlich R, Repple J, Grotegerd D, Meinert S, Hirsch JG, Niendorf T, Endemann B, Bamberg F, Kröncke T, Bülow R, Völzke H, von Stackelberg O, Sowade RF, Umutlu L, Schmidt B, Caspers S, Kugel H, Kircher T, Risse B, Gaser C, Cole JH, Dannlowski U, Berger K.
An uncertainty-aware, shareable, and transparent neural network architecture for brain-age modeling.
Sci Adv. 2022 8(1):eabg9471. PDF

Luders E, Gaser C, Gingnell M, Engman J, Sundström Poromaa I, Kurth F.
Postpartum Gray Matter Changes in the Auditory Cortex.
J Clin Med. 2021 10(23):5616. PDF

Broessner G, Ellerbrock I, Menz MM, Frank F, Verius M, Gaser C, May A.
Repetitive T1 Imaging Influences Gray Matter Volume Estimations in Structural Brain Imaging.
Front Neurol. 2021 12:755749. PDF

Kirschner M, Hodzic-Santor B, Antoniades M, Nenadic I, Kircher T, Krug A, Meller T, Grotegerd D, Fornito A, Arnatkeviciute A, Bellgrove MA, Tiego J, Dannlowski U, Koch K, Hülsmann C, Kugel H, Enneking V, Klug M, Leehr EJ, Böhnlein J, Gruber M, Mehler D, DeRosse P, Moyett A, Baune BT, Green M, Quidé Y, Pantelis C, Chan R, Wang Y, Ettinger U, Debbané M, Derome M, Gaser C, Besteher B, Diederen K, Spencer TJ, Fletcher P, Rössler W, Smigielski L, Kumari V, Premkumar P, Park HRP, Wiebels K, Lemmers-Jansen I, Gilleen J, Allen P, Kozhuharova P, Marsman JB, Lebedeva I, Tomyshev A, Mukhorina A, Kaiser S, Fett AK, Sommer I, Schuite-Koops S, Paquola C, Larivière S, Bernhardt B, Dagher A, Grant P, van Erp TGM, Turner JA, Thompson PM, Aleman A, Modinos G.
Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study.
Mol Psychiatry. 2022 27:1167-1176. PDF

Cherbuin N, Walsh EI, Shaw M, Luders E, Anstey KJ, Sachdev PS, Abhayaratna WP, Gaser C.
Optimal Blood Pressure Keeps Our Brains Younger.
Front Aging Neurosci. 2021 13:694982. PDF

Bussas M, Grahl S, Pongratz V, Berthele A, Gasperi C, Andlauer T, Gaser C, Kirschke JS, Wiestler B, Zimmer C, Hemmer B, Mühlau M.
Gray matter atrophy in relapsing-remitting multiple sclerosis is associated with white matter lesions in connecting fibers.
Mult Scler. 2021 28(6):900-909. PDF

Schmitz-Koep B, Haller B, Coupé P, Menegaux A, Gaser C, Zimmer C, Wolke D, Bartmann P, Sorg C, Hedderich DM.
Grey and White Matter Volume Changes after Preterm Birth: A Meta-Analytic Approach.
J Pers Med. 2021 11(9):868. PDF

Grahl S, Bussas M, Wiestler B, Eichinger P, Gaser C, Kirschke J, Zimmer C, Berthele A, Hemmer B, Mühlau M.
Differential Effects of Fingolimod and Natalizumab on Magnetic Resonance Imaging Measures in Relapsing-Remitting Multiple Sclerosis.
Neurotherapeutics 2021 18(4):2589-2597. PDF

Sevinc G, Rusche J, Wong B, Datta T, Kaufman R, Gutz SE, Schneider M, Todorova N, Gaser C, Thomalla G, Rentz D, Dickerson BD, Lazar SW.
Mindfulness Training Improves Cognition and Strengthens Intrinsic Connectivity Between the Hippocampus and Posteromedial Cortex in Healthy Older Adults.
Front Aging Neurosci. 2021 13:702796. PDF

Fisch L, Leenings R, Winter NR, Dannlowski U, Gaser C, Cole JH, Hahn T.
Editorial: Predicting Chronological Age From Structural Neuroimaging: The Predictive Analytics Competition 2019.
Front. Psychiatry. 2021 12:710932 PDF

Martins M, Reis AM, Castro SL, Gaser C.
Gray matter correlates of reading fluency deficits: SES matters, IQ does not.
Brain Struct Funct. 2021 226(8):2585-2601 PDF

Nenadic I, Lorenz C, Gaser C.
Narcissistic personality traits and prefrontal brain structure.
Sci. Rep. 2021 11(1):15707 PDF

Evermann U, Gaser C, Meller T, Pfarr JK, Grezellschak S, Nenadic I.
Nonclinical psychotic-like experiences and schizotypy dimensions: Associations with hippocampal subfield and amygdala volumes.
Hum Brain Mapp. 2021 42(15):5075-5088 PDF

Luders E, Gaser C, Gingnell M, Engman J, Sundström Poromaa I, Kurth F.
Significant increases of the amygdala between immediate and late postpartum: Pronounced effects within the superficial subregion.
J Neurosci Res. 2021 99(9):2261-2270 PDF

Steinbach R, Prell T, Gaur N, Roediger A, Gaser C, Mayer TE, Witte OW, Grosskreutz J.
Patterns of grey and white matter changes differ between bulbar and limb onset amyotrophic lateral sclerosis.
Neuroimage Clin. 2021 30:102674 PDF

Luders E, Gaser C, Gingnell M, Engman J, Sundström Poromaa I, Kurth F.
Gray matter increases within subregions of the hippocampal complex after pregnancy.
Brain Imaging Behav. 2021 15:2790-2794 PDF

Hedderich DM, Menegaux A, Schmitz-Koep B, Nuttall R, Zimmermann J, Schneider SC, Bäuml JG, Daamen M, Boecker H, Wilke M, Zimmer C, Wolke D, Bartmann P, Sorg C, Gaser C.
Increased Brain Age Gap Estimate (BrainAGE) in Young Adults After Premature Birth.
Front Aging Neurosci. 2021 13:653365 PDF

Jamalabadi H, Zuberer A, Kumar VJ, Li M, Alizadeh S, Amani AM, Gaser C, Esterman M, Walter M.
The missing role of gray matter in studying brain controllability.
Netw Neurosci. 2021 5(1):198-210 PDF

Delvecchio G, Maggioni E, Pigoni A, Crespo-Facorro B, Nenadic I, Benedetti F, Gaser C, Sauer H, Roiz-Santiañez R, Poletti S, Rossetti MG, Bellani M, Perlini C, Ruggeri M, Diwadkar VA, Brambilla P.
Sexual Regional Dimorphism of Post-Adolescent and Middle Age Brain Maturation. A Multi-center 3T MRI Study.
Front Aging Neurosci. 2021 13:622054 PDF

Bittner N, Jockwitz C, Franke K, Gaser C, Moebus S, Bayen UJ, Amunts K, Caspers S.
When your brain looks older than expected: combined lifestyle risk and BrainAGE.
Brain Struct Funct. 2021 226(3):621-645 PDF

Schmitt S, Besteher B, Gaser C, Nenadic I.
Human time perspective and its structural associations with voxel-based morphometry and gyrification.
Brain Imaging Behav. 2021 15(5):2237-2245 PDF

Schmidt S, Gull S, Herrmann KH, Boehme M, Irintchev A, Urbach A, Reichenbach JR, Klingner CM, Gaser C, Witte OW.
Experience-dependent structural plasticity in the adult brain: How the learning brain grows.
Neuroimage 2021 225:117502 PDF

Kurth F, Gaser C, Luders E.
Development of sex differences in the human brain.
Cogn Neurosci. 2021 12(3-4):155-162 PDF

2013-2020


Vickery S, Hopkins WD, Sherwood CC, Schapiro SJ, Latzman RD, Caspers S, Gaser C, Eickhoff SB, Dahnke R, Hoffstaedter F.
Chimpanzee brain morphometry utilizing standardized MRI preprocessing and macroanatomical annotations.
Elife 2020 9:e60136 PDF

Franke K, Bublak P, Hoyer D, Billiet T, Gaser C, Witte OW, Schwab M.
In vivo biomarkers of structural and functional brain development and aging in humans.
Neurosci Biobehav Rev. 2020 117:142-164 PDF

Schmitz-Koep B, Bäuml JG, Menegaux A, Nuttall R, Zimmermann J, Schneider SC, Daamen M, Scheef L, Boecker H, Zimmer C, Gaser C, Wolke D, Bartmann P, Sorg C, Hedderich DM.
Decreased cortical thickness mediates the relationship between premature birth and cognitive performance in adulthood.
Hum Brain Mapp. 2020 41(17):4952-4963 PDF

Evermann U, Gaser C, Besteher B, Langbein K, Nenadic I.
Cortical Gyrification, Psychotic-Like Experiences, and Cognitive Performance in Nonclinical Subjects.
Schizophr Bull. 2020 46(6):1524-1534 PDF

Seidel G, Gaser C, Götz T, Günther A, Hamzei F.
Accelerated brain ageing in sepsis survivors with cognitive long-term impairment.
Eur J Neurosci. 2020 52(10):4395-4402 PDF

Kharabian Masouleh S, Eickhoff SB, Zeighami Y, Lewis LB, Dahnke R, Gaser C, Chouinard-Decorte F, Lepage C, Scholtens LH, Hoffstaedter F, Glahn DC, Blangero J, Evans AC, Genon S, Valk SL.
Influence of Processing Pipeline on Cortical Thickness Measurement.
Cereb Cortex. 2020 30(9):5014-5027 PDF

Engl C, Tiemann L, Grahl S, Bussas M, Schmidt P, Pongratz V, Berthele A, Beer A, Gaser C, Kirschke JS, Zimmer C, Hemmer B, Mühlau M.
Cognitive Impairment in Early MS: Contribution of White Matter Lesions, Deep Grey Matter Atrophy, and Cortical Atrophy.
J Neurol. 2020 267(8):2307-2318 PDF

Luders E, Kurth F, Gingnell M, Engman J, Yong EL, Poromaa IS, Gaser C.
From baby brain to mommy brain: Widespread gray matter gain after giving birth.
Cortex. 2020 126, 334-342 PDF

Brodoehl S, Gaser C, Dahnke R, Witte OW, Klingner CM.
Surface-based analysis increases the specificity of cortical activation patterns and connectivity results.
Sci Rep. 2020 10 (1), 1-13 PDF

Nenadic I, Voss A, Besteher B, Langbein K, Gaser C.
Brain structure and symptom dimensions in borderline personality disorder.
Eur Psychiatry. 2020 63(1):e9 PDF

Steinbach R, Batyrbekova M, Gaur N, Voss A, Stubendorff B, Mayer TE, Gaser C, Witte OW, Prell T, Grosskreutz J.
Applying the D50 disease progression model to gray and white matter pathology in amyotrophic lateral sclerosis.
NeuroImage: Clin. 2020 25, 102094 PDF

Hedderich DM, Bäuml JG, Menegaux A, Avram M, Daamen M, Zimmer C, Bartmann P, Scheef L, Boecker H, Wolke D, Gaser C, Sorg C.
An analysis of MRI derived cortical complexity in premature-born adults: Regional patterns, risk factors, and potential significance.
NeuroImage 2020 208, 116438 PDF

Pigdon L, Willmott C, Reilly S, Conti-Ramsden G, Gaser C, Connelly A, Morgan AT.
Grey matter volume in developmental speech and language disorder.
Brain Struct Funct. 2019 224(9), 3387-3398 PDF

Pongratz V, Schmidt P, Bussas M, Grahl S, Gaser C, Berthele A, Hoshi MM, Kirschke J, Zimmer C, Hemmer B, Mühlau M.
Prognostic value of white matter lesion shrinking in early multiple sclerosis: An intuitive or naïve notion?
Brain Behav. 2019 9(12), e01417 PDF

Besteher B, Gaser C, Ivanšic D, Guntinas-Lichius O, Dobel C, Nenadic I.
Chronic tinnitus and the limbic system: Reappraising brain structural effects of distress and affective symptoms.
NeuroImage: Clin. 2019 24, 101976 PDF

Franke K, Gaser C.
Ten years of BrainAGE as a neuroimaging biomarker of brain aging: What insights have we gained?
Front Neurol. 2019 10, 789 PDF

Spalthoff R, Degenhardt F, Awasthi S, Heilmann-Heimbach S, Besteher B, Gaser C, Ripke S, Nöthen MM, Nenadic I.
Effects of a neurodevelopmental genes based polygenic risk score for schizophrenia and single gene variants on brain structure in non-clinical subjects: A preliminary report.
Schizophr Res. 2019 212, 225-228 PDF

Besteher B, Squarcina L, Spalthoff R, Bellani M, Gaser C, Brambilla P, Nenadic I.
Hippocampal Volume as a Putative Marker of Resilience or Compensation to Minor Depressive Symptoms in a Nonclinical Sample.
Front Psychiatry. 2019 10, 467 PDF

Besteher B, Gaser C, Nenadic I.
Brain Structure and Subclinical Symptoms: A Dimensional Perspective of Psychopathology in the Depression and Anxiety Spectrum.
Neuropsychobiology 2019 78 (3), 113-126 PDF

Besteher B, Gaser C, Nenadic I.
Machine-learning based brain age estimation in major depression showing no evidence of accelerated aging.
Psychiatry Res Neuroimaging 2019 290, 1-4 PDF

Schmidt P, Pongratz V, Küster P, Meier D, Wuerfel J, Lukas C, Bellenberg B, Zipp F, Groppa S, Sämann PG, Weber F, Gaser C, Franke T, Bussas M, Kirschke J, Zimmer C, Hemmer B, Mühlau M.
Automated segmentation of changes in FLAIR-hyperintense white matter lesions in multiple sclerosis on serial magnetic resonance imaging.
NeuroImage: Clin. 2019 23, 101849 PDF

Besteher B, Gaser C, Nenadic I.
Brain structure and trait impulsivity: A comparative VBM study contrasting neural correlates of traditional and alternative concepts in healthy subjects.
Neuropsychologia. 2019 131, 139-147 PDF

Hedderich DM, Bäuml JG, Berndt MT, Menegaux A, Scheef L, Daamen M, Zimmer C, Bartmann P, Boecker H, Wolke D, Gaser C, Sorg C.
Aberrant gyrification contributes to the link between gestational age and adult IQ after premature birth.
Brain. 2019 142 (5), 1255-1269 PDF

Lotze M, Domin M, Gerlach FH, Gaser C, Lueders E, Schmidt CO, Neumann N.
Novel findings from 2,838 adult brains on sex differences in gray matter brain volume.
Sci Rep. 2019 9 (1), 1-7 PDF

Eyme KM, Domin M, Gerlach FH, Hosten N, Schmidt CO, Gaser C, Flöel A, Lotze M.
Physically active life style is associated with increased grey matter brain volume in a medial parieto-frontal network.
Behav Brain Res. 2019 359, 215-222 PDF

Besteher B, Squarcina L, Spalthoff R, Bellani M, Gaser C, Nenadic I, Brambilla P.
Subclinical agoraphobia symptoms and regional brain volumes in non-clinical subjects: between compensation and resilience?
Front Psychiatry. 2018 9, 541 PDF

Spalthoff R, Gaser C, Nenadic I.
Altered gyrification in schizophrenia and its relation to other morphometric markers.
Schizophr Res. 2018 202:195-202 PDF

Luders E, Gingnell M, Poromaa IS, Engman J, Kurth F, Gaser C.
Potential Brain Age Reversal after Pregnancy: Younger Brains at 4-6 Weeks Postpartum.
Neuroscience 2018 386: 309-314 PDF

Scheller E, Schumacher LV, Peter J, Lahr J, Wehrle J, Kaller CP, Gaser C, Klöppel S.
Brain Aging and APOE e4 Interact to Reveal Potential Neuronal Compensation in Healthy Older Adults.
Front Aging Neurosci. 2018 10: 74 PDF

Langbein K, Hesse J, Gussew A, Milleit B, Lavoie S, Amminger GP, Gaser C, Wagner G, Reichenbach JR, Hipler UC, Winter D, Smesny S.
Disturbed glutathione antioxidative defense is associated with structural brain changes in neuroleptic-naïve first-episode psychosis patients.
Prostaglandins Leukot Essent Fatty Acids 2018 136:103-110 PDF

Franke K, Gaser C, Roseboom TJ, Schwab M, de Rooij SR.
Premature brain aging in humans exposed to maternal nutrient restriction during early gestation.
Neuroimage. 2018 173:460-471 PDF

Rogenmoser L, Kernbach J, Schlaug G, Gaser C.
Keeping brains young with making music.
Brain Struct Funct. 2018 223(1):297-305 PDF

Maggioni E, Crespo-Facorro B, Nenadic I, Benedetti F, Gaser C, Sauer H, Roiz-Santiañez R, Poletti S, Marinelli V, Bellani M, Perlini C, Ruggeri M, Altamura AC, Diwadkar VA, Brambilla P; ENPACT group.
Common and distinct structural features of schizophrenia and bipolar disorder: The European Network on Psychosis, Affective disorders and Cognitive Trajectory (ENPACT) study.
PLoS ONE. 2017 12(11): e0188000 PDF

Besteher B, Squarcina L, Spalthoff R, Bellani M, Gaser C, Brambilla P, Nenadic I.
Brain structural correlates of irritability: Findings in a large healthy cohort.
Hum Brain Mapp. 2017 38(12): 6230-6238 PDF

Steinke J, Gaser C, Langbein K, Dietzek M, Gussew A, Reichenbach JR, Smesny S, Sauer H, Nenadic I.
Hippocampal metabolism and prefrontal brain structure: a combined 1H-MR spectroscopy, neuropsychological, and voxel-based morphometry (VBM) study.
Brain Res. 2017 1677: 14-10 PDF

Besteher B, Gaser C, Spalthoff R, Nenadic I.
Associations between urban upbringing and cortical thickness and gyrification.
J Psychiatr Res. 2017 95: 114-120 PDF

Righart R, Schmidt P, Dahnke R, Biberacher V, Beer A, Buck D, Hemmer B, Kirschke JS, Zimmer C, Gaser C, Mühlau M.
Volume versus surface-based cortical thickness measurements: A comparative study with healthy controls and multiple sclerosis patients.
Brain Struct Funct. 2017 12(7): e0179590 PDF

Nenadic I, Dietzek M, Langbein K, Sauer H, Gaser C.
BrainAGE score indicates accelerated brain aging in schizophrenia, but not bipolar disorder.
Psychiatry Res. 2017 266: 86-89 PDF

Franke K, Clarke GD, Dahnke R, Gaser C, Kuo AH, Li C, Schwab M, Nathanielsz PW.
Premature Brain Aging in Baboons Resulting from Moderate Fetal Undernutrition.
Front Aging Neurosci. 2017 9: 92 PDF

Nenadic I, Yotter RA, Dietzek M, Langbein K, Sauer H, Gaser C.
Cortical complexity in bipolar disorder applying a spherical harmonics approach.
Psychiatry Res. 2017 263: 44-47 PDF

Besteher B, Gaser C, Langbein K, Dietzek M, Sauer H, Nenadic I.
Effects of subclinical depression, anxiety and somatization on brain structure in healthy subjects.
J Affect Disord. 2017 215: 111-117 PDF

L. C. Loewe, C. Gaser, K. Franke, Alzheimer’s Disease Neuroimaging Initiative.
The Effect of the APOE Genotype on Individual BrainAGE in Normal Aging, Mild Cognitive Impairment, and Alzheimer’s Disease.
PLoS ONE, 11(7): e015754, 2016. PDF

E. Luders, N. Cherbuin, C. Gaser.
Estimating brain age using high-resolution pattern recognition: Younger brains in long-term meditation practitioners.
Neuroimage, 134: 508-53, 2016. PDF

B. Kleber, R. Veit, M. Rothermund, C.V. Moll, C. Gaser, N. Birbaumer, M. Lotze.
Voxel-based morphometry in opera singers: Increased gray-matter volume in right somatosensory and auditory cortices.
Neuroimage, 133: 477-483, 2016. PDF

B. Milleit, S. Smesny, M. Rothermund, C. Preul, M.L. Schroeter, C. von Eiff, G. Ponath, C. Milleit, H. Sauer, C. Gaser.
Serum S100B Protein is Specifically Related to White Matter Changes in Schizophrenia.
Front Cell Neurosci, 6: 10:33, 2016. PDF

S. Smesny, A. Gussew, N.J. Biesel, S. Schack, M. Walther, R. Rzanny, B. Milleit, C. Gaser, T. Sobanski, C.C. Schultz, P. Amminger, U.-C. Hipler, H. Sauer, J.R. Reichenbach.
Glutamatergic dysfunction linked to energy and membrane lipid metabolism in frontal and anterior cingulate cortices of never treated first-episode schizophrenia patients.
Schizophr Res, 168(1-2): 322-329, 2015. PDF

I. Nenadic, C. Lorenz, K. Langbein, M. Dietzek, S. Smesny, N. Schönfeld, L. Fañanás, H. Sauer, C. Gaser.
Brain structural correlates of schizotypy and psychosis proneness in a non-clinical healthy volunteer sample.
Schizophr Res, 168(1-2): 37-43, 2015. PDF

I. Nenadic, R. Maitra, M. Dietzek, K. Langbein, S. Smesny, H. Sauer, C. Gaser.
Prefrontal gyrification in psychotic bipolar I disorder vs. schizophrenia.
J Affect Disord, 185: 104-107, 2015. PDF

I. Nenadic, R. Maitra, S. Basu, M. Dietzek, N. Schönfeld, C. Lorenz, A. Gussew, P. Aminger, P. McGorry, J.R. Reichenbach, H. Sauer, C. Gaser, S. Smesny.
Associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia.
Eur Neuropsychopharmacol, 25(10): 1661-1668, 2015. PDF

I. Nenadic, R. Maitra, K. Langbein, M. Dietzek, C. Lorenz, S. Smesny, J.R. Reichenbach, H. Sauer, C. Gaser.
Brain structure in schizophrenia vs. psychotic bipolar I disorder: A VBM study.
Schizophr Res, 165(2-3): 212-219, 2015. PDF

K. Franke, G. Hagemann, E. Schleussner, C. Gaser.
Changes of individual BrainAGE during the course of the menstrual cycle.
NeuroImage, 115: 1-6, 2015. PDF

I. Nenadic, R.A. Yotter, H. Sauer, C. Gaser.
Patterns of cortical thinning in different subgroups of schizophrenia.
Br J Psychiatry, 206(6): 479-483, 2015. PDF

E.E. Bron, M. Smits, W.M. van der Flier, H. Vrenken, F. Barkhof, P. Scheltens, J.M. Papma, R.M.E. Steketee, C. Méndez Orellana, R. Meijboom, M. Pinto, J.R. Meireles, C. Garrett, A.J. Bastos-Leite, A. Abdulkadir, O. Ronneberger, N. Amoroso, R. Bellotti, D. Cárdenas-Peña, A.M. Álvarez-Meza, C.V. Dolph, K.M. Iftekharuddin, S.F. Eskildsen, P. Coupé, V.S. Fonov, K. Franke, C. Gaser, C. Ledig, R. Guerrero, T. Tong, K.R. Gray, E. Moradi, J. Tohka, A. Routier, S. Durrleman, A. Sarica, G. Di Fatta, F. Sensi, A. Chincarini, G.M. Smith, Z.V. Stoyanov, L. Sørensen, M. Nielsen, S. Tangaro, P. Inglese, C. Wachinger, M. Reuter, J.C. van Swieten, W.J. Niessen, S. Klein
Standardized evaluation of algorithms for computer-aided diagnosis of dementia based on structural MRI: The CADDementia challenge.
NeuroImage, 111: 562-579, 2015. PDF

F. Kurth, C. Gaser, E. Luders.
A 12-step user guide for analyzing voxel-wise gray matter asymmetries in statistical parametric mapping (SPM).
Nature Protocols, 10: 293-304, 2015. PDF

I. Nenadic, M. Dietzek, N. Schönfeld, C. Lorenz, A. Gussew, J.R. Reichenbach, H. Sauer, C. Gaser, S. Smesny.
Brain structure in people at ultra-high risk of psychosis, patients with first-episode schizophrenia, and healthy controls: a VBM study.
Schizophrenia Res, 161(2-3): 169-176, 2015. PDF

I. Nenadic, D. Güllmar, M. Dietzek, K. Langbein, J. Steinke, C. Gaser.
Brain structure in narcissistic personality disorder: A VBM and DTI pilot study.
Psychiatry Res, 231(2): 184-186, 2015. PDF

E. Moradi, A. Pepe, C. Gaser, H. Huttunen, J. Tohka.
Machine learning framework for early MRI-based Alzheimer’s conversion prediction in MCI subjects.
NeuroImage, 104: 398-412, 2015. PDF

I. Nenadic, R. Maitra, F.B. Basmanav, C.C. Schultz, C. Lorenz, C. Schachtzabel, S. Smesny, M.M. Nöthen, S. Cichon, J.R. Reichenbach, H. Sauer, R.G. Schlösser, C. Gaser.
ZNF804A genetic variation (rs1344706) affects brain grey but not white matter in schizophrenia and healthy subjects.
Psychological Medicine, 45(1): 143-152, 2015. PDF

V. Hartung, T. Prell, C. Gaser, M.R. Turner, F. Tietz, B. Ilse, M. Bokemeyer, O.W. Witte, J. Grosskreutz.
Voxel-based MRI intensitometry reveals extent of cerebral white matter pathology in amyotrophic lateral sclerosis.
PLoS ONE, 9(8): e104894, 2014. PDF

K. Franke, M. Ristow, C. Gaser.
Gender-specific impact of personal health parameters on individual brain aging in cognitively unimpaired elderly subjects.
Front Aging Neurosci, 6: 94, 2014. PDF

G. Ziegler, G. Ridgway, R. Dahnke, C. Gaser.
Individualized Gaussian process-based prediction and detection of local and global gray matter abnormalities in elderly subjects.
NeuroImage, 97: 333-348, 2014. PDF

F. Kurth, E. Luders, N.L. Sicotte, C. Gaser, B.S. Giesser, R.S. Swerdloff, M.J. Montag, R.R. Voskuhl, A. Mackenzie-Graham.
Neuroprotective effects of testosterone treatment in men with multiple sclerosis.
NeuroImage Clinical, 4(2014): 454-460, 2014. PDF

W. Freund, S. Faust, C. Gaser, G. Groen, F. Birklein, A.P. Wunderlich, M. Mueller, C. Billich, U.H. Schuetz.
Regionally accentuated reversible brain grey matter reduction in ultra marathon runners detected by voxel-based morphometry.
BMC Sports Science, Medicine and Rehabilitation, 6: 4, 2014. PDF

N. Koutsouleris, C. Davatzikos, S. Borgwardt, C. Gaser, R. Bottlender, T. Frodl, P. Falkai, A. Riecher-Rössler, H.-J. Möller, M. Reiser, C. Pantelis, E.M. Meisenzahl.
Accelerated Brain Aging in Schizophrenia and Beyond: A Neuroanatomical Marker of Psychiatric Disorders.
Schizophrenia Bulletin, 40(5): 1140-1153, 2014. PDF

I. Nenadic, R.A. Yotter, H. Sauer, C. Gaser.
Cortical surface complexity in frontal and temporal areas varies across subgroups of schizophrenia.
Human Brain Mapping, 35(4): 1691-1699, 2014. PDF

K. Franke, C. Gaser, B. Manor, V. Novak.
Advanced BrainAGE in older adults with type 2 diabetes mellitus.
Front Aging Neurosci, 5: 90, 2013. PDF

G. Wagner, K. Koch, C. Schachtzabel, C.C. Schultz, C. Gaser, J.R. Reichenbach, H. Sauer, K.-J. Bär, R.G. Schlösser.
Structural basis of the fronto-thalamic dysconnectivity in schizophrenia: A combined DCM-VBM study.
NeuroImage: Clinical, 3: 95-105, 2013. PDF

E. Luders, F. Kurth, A.W. Toga, K.L. Narr, C. Gaser.
Meditation effects within the hippocampal complex revealed by voxel-based morphometry and cytoarchitectonic probabilistic mapping.
Frontiers in Psychology, 4(1):398, 2013. PDF

P. Schmidt, V.J. Schmid, C. Gaser, D. Buck, S. Bührlen, A. Föschler, M. Mühlau.
Fully Bayesian inference for structural MRI: application to segmentation and statistical analysis of T2-hypointensities in healthy subjects.
PLoS ONE, 8(7): e68196, 2013. PDF

G. Ziegler, R. Dahnke, A.D. Winkler, C. Gaser.
Partial Least Squares Correlation of Multivariate Cognitive Abilities and Local Brain Structure in Children and Adolescents.
NeuroImage, 82: 284-294, 2013. PDF

C. Gaser, K. Franke, S. Klöppel, N. Koutsouleris, H. Sauer, Alzheimer’s Disease Neuroimaging Initiative.
BrainAGE in mild cognitive impaired patients: predicting the conversion to Alzheimer’s disease.
PLoS ONE, 8(6): e67346, 2013. PDF

M. Mühlau, D. Buck, A. Förschler, C.C. Boucard, M. Arsic, P. Schmidt, C. Gaser, A. Berthele, M. Hoshi, A. Jochim, H. Kronsbein, C. Zimmer, B. Hemmer, R. Ilg.
Multiple Sclerosis Journal, 19(11): 1485-92, 2013. PDF

C.C. Schultz, G. Wagner, K. Koch, C. Gaser, M. Roebel, C. Schachtzabel, I. Nenadic, J.R. Reichenbach, H. Sauer, R.G. Schlösser.
The visual cortex in schizophrenia: alterations of gyrification rather than cortical thickness-a combined cortical shape analysis.
Brain Struct Funct, 218(1): 5-8, 2013. PDF

2005-2012


G. Mingoia, K. Langbein, M. Dietzek, G. Wagner, S. Smesny, R. Maitra, J.R. Reichenbach, R.G.M. Schlösser, C. Gaser, H. Sauer, I. Nenadic.
Frequency domains of resting state default mode network activity in schizophrenia.
Psychiatry Research: Neuroimaging, 138(2-3): 143-149, 2012. PDF

W. Freund, S. Faust, F. Birklein, C. Gaser, A.P. Wunderlich, M. Mueller, C. Billich, M. Juchems, B.L. Schmitz, G. Groen, U.H. Schuetz.
Substantial and reversible brain grey matter reduction but no acute brain lesions in ultra marathon runners. Experience from the TransEurope FootRace Project.
BMC Medicine, 10: 170, 2012. PDF

I. Nenadic, R. Maitra, S. Scherpiet, C. Gaser, C.C. Schultz, C. Schachtzabel, S. Smesny, J.R. Reichenbach, J. Treutlein, T.W. Mühleisen, T. Deufel, S. Cichon, M. Rietschel, M.M. Nöthen, H. Sauer, R.G.M. Schlösser.
Glutamate receptor delta 1 (GRID1) genetic variation and brain structure in schizophrenia.
Journal of Psychiatric Research, 46(12): 1531-1539, 2012. PDF

K. Franke, C. Gaser.
Longitudinal changes in individual BrainAGE in healthy aging, mild cognitive impairment, and Alzheimer’s disease.
The Journal of Gerontopsychology and Geriatric Psychiatry, 25(4): 235-245, 2012. PDF

R. Dahnke, R. Yotter, C. Gaser.
Cortical thickness and central surface estimation.
Neuroimage, 65: 336-348, 2012. PDF

E. Luders, F.J. Sánchez, D. Tosun, D.W. Shattuck, C. Gaser, E. Vilain, A.W. Toga.
Increased Cortical Thickness in Male-to-Female Transsexualism.
Journal of Behavioral and Brain Science, 2(3): 357-362, 2012. PDF

K. Franke, E. Luders, A. May, M. Wilke, C. Gaser.
Brain maturation: Predicting individual BrainAGE in children and adolescents using structural MRI.
Neuroimage, 63(3): 1305-1312, 2012. PDF

I. Nenadic, C. Gaser, H. Sauer.
Heterogeneity of brain structural variation and the structural imaging endophenotypes in schizophrenia.
Neuropsychobiology, 66(1): 44-9, 2012. PDF

C. Gaser, S. Schmidt, M. Metzler, K.-H. Herrmann, I. Krumbein, J.R. Reichenbach, O.W. Witte.
Deformation-based brain morphometry in rats.
NeuroImage, 63(1): 47-53, 2012. PDF

G. Mingoia, G. Wagner, K. Langbein, R. Maitra, S. Smesny, M. Dietzek, H.P. Burmeister, J.R. Reichenbach, R.G.M. Schlösser, C. Gaser, H. Sauer, I. Nenadic.
Default mode network activity in schizophrenia studied at resting state using probabilistic ICA.
Schizophrenia Research, 138(2-3): 143-9, 2012. PDF

G. Ziegler, R. Dahnke, C. Gaser.
Models of the aging brain structure and individual decline.
Frontiers in Neuroinformatics, 6: 3, 2012. PDF

E. Luders, F. Kurth, E.A. Mayer, A.W. Toga, K.L. Narr, C. Gaser.
The unique brain anatomy of meditation practitioners: alterations in cortical gyrification.
Frontiers in Human Neuroscience, 6: 34, 2012. PDF

M. Mühlau, J. Winkelmann, D. Rujescu, I. Giegling, N. Koutsouleris, C. Gaser, M. Arsic, A. Weindl, M. Reiser, E.M. Meisenzahl.
Variation within the Huntington’s Disease Gene Influences Normal Brain Structure.
PLoS ONE 7(1): e29809, 2012. PDF

A. May, C. Gaser.
Response to Thomas and Baker: the structural adaptation of the brain to training.
Trends Cogn Sci., 16(2): 97-8, 2012. PDF

P. Schmidt, C. Gaser, M. Arsic, D. Buck, A. Förschler, A. Berthele, M. Hoshi, R. Ilg, V.J. Schmid, C. Zimmer, B. Hemmer, M. Mühlau.
An automated tool for detection of FLAIR-hyperintense white-matter lesions in Multiple Sclerosis.
Neuroimage, 59(4): 3774-83, 2012. PDF

K.-H. Herrmann, S. Schmidt, A. Kretz, R. Haenold, I. Krumbein, M. Metzler, C. Gaser, O.W. Witte, J.R. Reichenbach.
Possibilities and limitations for high resolution small animal MRI on a clinical whole-body 3T scanner.
Magn Reson Mater Phy, 25(3): 233-244, 2012. PDF

N. Koutsouleris, C. Gaser, K. Patschurek-Kliche, J. Scheuerecker, R. Bottlender, P. Decker, G. Schmitt, M. Reiser, H.-J. Möller, E.M. Meisenzahl.
Multivariate patterns of brain–cognition associations relating to vulnerability and clinical outcome in the at-risk mental states for psychosis.
Human Brain Mapping,33(9): 2104-24, 2012. PDF

G. Ziegler, R. Dahnke, L. Jäncke, R.A. Yotter, A. May, C. Gaser.
Brain structural trajectories over the adult lifespan.
Human Brain Mapping, 33(10): 2377-89, 2012. PDF

I. Nenadic, H. Sauer, S. Smesny, C. Gaser.
Aging effects on regional brain structural changes in schizophrenia.
Schizophrenia Bulletin, 38(4): 838-44, 2012. PDF

N. Koutsouleris, C. Davatzikos, R. Bottlender, K. Patschurek-Kliche, J. Scheuerecker, P. Decker, C. Gaser, H.-J. Möller, E.M. Meisenzahl.
Early Recognition and Disease Prediction in the At-Risk Mental States for Psychosis Using Neurocognitive Pattern Classification.
Schizophrenia Bulletin, 38(6): 1200-15, 2012. PDF

L. Bezzola L, S. Mérillat, C. Gaser, L. Jäncke.
Training-induced neural plasticity in golf novices.
Journal of Neuroscience, 31(35): 12444-8, 2011. PDF

M.R. Turner, J. Grosskreutz, J. Kassubek, S. Abrahams, F. Agosta, M. Benatar, M. Filippi, L.H. Goldstein, M. van den Heuvel, S. Kalra, D. Lulé, B. Mohammadi, for the first Neuroimaging Symosium in ALS (NISALS).
Towards a neuroimaging biomarker for amyotrophic lateral sclerosis.
The Lancet Neurology, 10(5): 400-403, 2011. PDF

T. Bitter, H. Gudziol, H.P. Burmeister, H.-J. Mentzel, C. Gaser, O. Guntinas-Lichius.
Volume alterations in the gray matter of anosmic subjects : Lessons we can learn from voxel-based morphometry.
HNO, 59(3): 248-254, 2011. PDF

S. Derflinger, C. Sorg, C. Gaser, N. Myers, M. Arsic, A. Kurz, C. Zimmer, A. Wohlschläger, M. Mühlau.
Grey-Matter Atrophy in Alzheimer’s Disease is Asymmetric but not Lateralized.
Journal of Alzheimers Disease, 25: 347-357, 2011. PDF

G. Hagemann, T. Ugur, E. Schleussner, H.-J. Mentzel, C. Fitzek, O.W. Witte, C. Gaser.
Changes in Brain Size during the Menstrual Cycle.
PLoS ONE, 6(2): e14655, 2011. PDF

T. Bitter, F. Siegert, H. Gudziol, H.P. Burmeister, H.-J. Mentzel, T. Hummel, C. Gaser, O. Guntinas-Lichius.
Gray matter alterations in parosmia.
Neuroscience, 177: 177-82, 2011. PDF

R.A. Yotter, G. Ziegler, I. Nenadic, P.M. Thompson, C. Gaser
Local cortical surface complexity maps from spherical harmonic reconstructions.
Neuroimage, 56(3): 961-973, 2011. PDF

O. Granert, M. Peller, C. Gaser, S. Groppa, M. Hallett, A. Knutzen, G. Deuschl, K.E. Zeuner, H.R. Siebner.
Manual activity shapes structure and function in contralateral human motor hand area.
Neuroimage, 54(1): 32-41, 2011. PDF

R.A. Yotter, R. Dahnke, P.M. Thompson, C. Gaser.
Topological Correction of Brain Surface Meshes Using Spherical Harmonics.
Human Brain Mapping, 32(7): 1109-24, 2011. PDF

R.A. Yotter, P.M. Thompson, C. Gaser.
Algorithms to Improve the Re-Parameterization of Spherical Mappings of Brain.
Journal of Neuroimaging, 21(2):e134-47, 2011. PDF

R.A. Yotter, P.M. Thompson, I. Nenadic, C. Gaser.
Estimating local surface complexity maps using spherical harmonic reconstructions.
Med Image Comput Comput Assist Interv, 13(2): 169–176, 2010. PDF

C.C. Schultz, K. Koch, G. Wagner, M. Roebel, I. Nenadic, C. Gaser, C. Schachtzabel, J.R. Reichenbach, H. Sauer, R.G. Schlösser.
Increased parahippocampal and lingual gyrification in first-episode schizophrenia.
Schizophrenia Research, 123(2-3): 137–144, 2010. PDF

N. Koutsouleris, K. Patschurek-Kliche, J. Scheuerecker, P. Decker, R. Bottlender, G. Schmitt, R. Rujescu, I. Giegling, C. Gaser, M. Reiser, H.-J. Möller, E.M. Meisenzahl.
Neuroanatomical correlates of executive dysfunction in the at-risk mental state for psychosis.
Schizophrenia Research, 123(2-3): 160-174, 2010. PDF

N. Koutsouleris, C. Gaser, R. Bottlender, C. Davatzikos, P. Decker, M. Jäger, G. Schmitt, M. Reiser, H.-J. Möller, E.M. Meisenzahl.
Use of Neuroanatomical Pattern Regression to Predict the Structural Brain Dynamics of Vulnerability and Transition to Psychosis.
Schizophrenia Research, 123(2-3): 175-187, 2010. PDF

S. Smesny, B. Milleit, I. Nenadic, C. Preul, D. Kinder, J. Lasch, I. Willhardt, H. Sauer, C. Gaser.
Phospholipase A(2) activity is associated with structural brain changes in schizophrenia.
Neuroimage, 52(4): 1314-1327, 2010. PDF

T. Bitter, J. Brüderle, H. Gudziol, H.P. Burmeister, C. Gaser, O. Guntinas-Lichius.
Gray and white matter reduction in hyposmic subjects – a voxel-based morphometry study.
Brain Research, 1347: 42-47, 2010. PDF

E. Gaser, C. Gaser, M. Rahming, T. Weiss, W. Meissner.
Enhanced tactile resolution of the contralateral side after surgery and regional anesthesia of the hand.
Neuroreport, 21(16): 1013-1017, 2010.

K. Reetz, R. Lencer, J.M. Hagenah, C. Gaser, V. Tadic, U. Walter, A. Wolters, S. Steinlechner, C. Zühlke, K. Brockmann, C. Klein, A. Rolfs, F. Binkofski.
Structural Changes Associated with Progression of Motor Deficits in Spinocerebellar Ataxia 17.
Cerebellum, 9(2): 210-217, 2010. PDF

T. Bitter, H. Gudziol, H.P. Burmeister, H.-J. Mentzel, O. Guntinas-Lichius, C. Gaser.
Anosmia Leads to a Loss of Gray Matter in Cortical Brain Areas.
Chemical Senses, 35(5): 407-415, 2010. PDF

K. Franke, G. Ziegler, S. Klöppel, C. Gaser.
Estimating the age of healthy subjects from T1-weighted MRI scans using kernel methods: Exploring the influence of various parameters.
Neuroimage, 50(3): 883-892, 2010. PDF

I. Nenadic, S. Smesny, R.G. Schlösser, H. Sauer, C. Gaser.
Auditory hallucinations and brain structure in schizophrenia: a VBM study.
British Journal of Psychiatry, 196: 412-413, 2010. PDF

C.C. Schultz, K. Koch, G. Wagner, M. Roebel, C. Schachtzabel, C. Gaser, I. Nenadic, J.R. Reichenbach, H. Sauer, R.G. Schlösser.
Reduced cortical thickness in first episode schizophrenia.
Schizophrenia Research 116(2-3): 204-209, 2010. PDF

I. Nenadic, H. Sauer, C. Gaser.
Distinct pattern of brain structural deficits in sub-syndromes of schizophrenia delineated by psychopathology.
Neuroimage, 49(2): 1153-1160, 2010. PDF

R.A. Yotter, R. Dahnke, C. Gaser.
Topological Correction of Brain Surface Meshes Using Spherical Harmonics.
Med Image Comput Comput Assist Interv, 12(2): 125–132, 2009. PDF

E. Luders, C. Gaser, K.L. Narr, A.W. Toga.
Why sex matters: Brain size independent differences in gray matter distribution between men and women.
Journal of Neuroscience, 29: 14265-14270, 2009. PDF

D. Mietchen, C. Gaser.
Computational morphometry for detecting changes in brain structure due to development, aging, learning, disease and evolution.
Frontiers in Neuroinformatics, 3: 25, 2009. PDF

E. Luders, F. J. Sanchez, C. Gaser, A.W. Toga, K.L. Narr, L.S. Hamilton, E. Vilain.
Regional gray matter variation in male-to-female transsexualism.
Neuroimage, 46(4): 904-907, 2009, PDF

N. Koutsouleris, E.M. Meisenzahl, C. Davatzikos, R. Bottlender, T. Frodl, J. Scheuerecker, G.E. Schmitt, B. Burgermeister, M. Reiser, H-J. Möller, C. Gaser.
Neuroanatomical pattern classification identifies subjects in at-risk mental states of psychosis and predicts disease transition.
Archives of General Psychiatry, 66(7): 700-712, 2009. PDF

N. Koutsouleris, G. Schmitt, C. Gaser, R. Bottlender, J. Scheuerecker, P.K. McGuire, B. Burgermeister, C. Born, M. Reiser, H.-J. Moeller, E.M. Meisenzahl.
Neuroanatomical correlates of different vulnerability states of psychosis in relation to clinical outcome.
British Journal of Psychiatry, 195(3): 218-226, 2009. PDF

E. Luders, A.W. Toga, N. Lepore, C. Gaser.
The underlying anatomical correlates of long-term meditation: Larger hippocampal and frontal volumes of gray matter.
Neuroimage, 45(3): 672-678, 2009. PDF

K. Reetz, C. Gaser, C. Klein, J. Hagenah, C. Büchel, S. Gottschalk, P.P. Pramstaller, H.R. Siebner, F. Binkofski.
Structural findings in the basal ganglia in genetically determined and idiopathic Parkinson’s disease.
Movement Disorders, 24(1): 99-103, 2009. PDF

S. Nunnemann, A.M. Wohlschlager, R. Ilg, C. Gaser, T. Etgen, B. Conrad, C. Zimmer, M. Muhlau.
Accelerated aging of the putamen in men but not in women.
Neurobiology of Aging, 30(1): 147-151, 2009. PDF

M. Mühlau, A.M. Wohlschläger, C. Gaser, M. Valet, A. Weindl, S. Nunnemann, A. Peinemann, T. Etgen, R. Ilg.
Voxel-based morphometry in individual patients: a pilot study in early Huntington’s disease.
American Journal of Neuroradiology, 30(3): 539-543, 2009. PDF

K. Reetz, H.R. Siebner, C. Gaser, J. Hagenah, C. Büchel, M. Kasten, D. Petersen, P.P. Pramstaller, C. Klein, F. Binkofski.
Premotor Gray Matter Volume is Associated with Clinical Findings in Idiopathic and Genetically Determined Parkinson’s Disease.
The Open Neuroimaging Journal, 2: 102-105, 2008. PDF

M. Altaye, S.K. Holland, M. Wilke, C. Gaser.
Infant Brain Probability Templates for MRI Segmentation and Normalization.
Neuroimage, 43: 721-730, 2008. PDF

J. Driemeyer, J. Boyke, C. Gaser, C. Büchel, A. May.
Changes in gray matter induced by learning–revisited.
PLoS ONE, 3(7): e2669, 2008. PDF

J. Boyke, J. Driemeyer, C. Gaser, C. Büchel, A. May.
Training-Induced Brain Structure Changes in the Elderly.
Journal of Neuroscience, 28(28): 7031-7035, 2008. PDF
This week in Journal of Neuroscience

E.M. Meisenzahl, N. Koutsouleris, C. Gaser, R. Bottlender, G.J.E. Schmitt, P. McGuire, P. Decker, B. Burgermeister, C. Born, M. Reiser, H.-J. Möller.
Structural brain alterations in subjects at high-risk of psychosis: A voxel-based morphometric study.
Schizophrenia Research, 102(1-3): 150-162, 2008. PDF

M. Wilke, S.K. Holland, M. Altaye, C. Gaser.
Template-O-Matic: A toolbox for creating customized pediatric templates.
Neuroimage, 41(3): 903-913, 2008. PDF

R. Ilg, A.M. Wohlschlager, C. Gaser, Y. Liebau, R. Dauner, A. Woller, C. Zimmer, J. Zihl, M. Muhlau.
Gray Matter Increase Induced by Practice Correlates with Task-Specific Activation: A Combined Functional and Morphometric Magnetic Resonance Imaging Study.
Journal of Neuroscience, 28(16): 4210-4215, 2008. PDF

K. Reetz, R. Lenzer, S. Steinlechner, C. Gaser, J. Hagenah, C. Büchel, D. Petersen, N. Kock, A. Djarmati, H.R. Siebner, C. Klein, F. Binkofski.
Limbic and Frontal Cortical Degeneration Is Associated with Psychiatric Symptoms in PINK1 Mutation Carriers.
Biological Psychiatry, 64(3): 241-247, 2008. PDF

E. Luders, K.L. Narr, R.M. Bilder, P.R. Szeszko, M.N. Gurbani, L. Hamilton, A.W. Toga, C. Gaser.
Mapping the Relationship between Cortical Convolution and Intelligence: Effects of Gender.
Cerebral Cortex, 18: 2019-2026, 2008. PDF

N. Koutsouleris, C. Gaser, M. Jäger, R. Bottlender, T. Frodl, S. Holzinger, G.J.E. Schmitt, T. Zetzsche, B. Burgermeister, J. Scheuerecker, C. Born, M. Reiser, H.-J. Möller, E.M. Meisenzahl.
Structural correlates of psychopathological symptom dimensions in schizophrenia: A voxel-based morphometric study.
Neuroimage, 39(4): 1600-1612, 2008. PDF

M. Muhlau, C. Gaser, R. Ilg, B. Conrad, C. Leibl, M.H. Cebulla, H. Backmund, M. Gerlinghoff, P. Lommer, A. Schnebel, A.M. Wohlschlager, C. Zimmer, S. Nunnemann.
Gray Matter Decrease of the Anterior Cingulate Cortex in Anorexia Nervosa.
American Journal of Psychiatry, 164(12): 1850-1857, 2007. PDF

F. Binkofski, K. Reetz, C. Gaser, R. Hilker, J. Hagenah, K. Hedrich, T. van Eimeren, A. Thiel, C. Buchel, P.P. Pramstaller, H.R. Siebner, C. Klein.
Morphometric fingerprint of asymptomatic Parkin and PINK1 mutation carriers in the basal ganglia.
Neurology, 69(9): 842-50, 2007. PDF

M. Muhlau, C. Gaser, A.M. Wohlschlager, A. Weindl, M. Stadtler, M. Valet, C. Zimmer, J. Kassubek, A. Peinemann.
Striatal gray matter loss in Huntington’s disease is leftward biased.
Movement Disorders, 22(8): 1169-1201, 2007. PDF

C. Soriano-Mas, J. Pujol, P. Alonso, N. Cardoner, J.M. Menchon, B. J. Harrison, J. Deus, J. Vallejo, C. Gaser.
Identifying patients with obsessive-compulsive disorder using whole-brain anatomy.
Neuroimage, 35(3): 1028-1037, 2007. PDF

M. Muhlau, A. Weindl, A.M. Wohlschlager, C. Gaser, M. Stadtler, M. Valet, C. Zimmer, J. Kassubek, A. Peinemann.
Voxel-based morphometry indicates relative preservation of the limbic prefrontal cortex in early Huntington disease.
Journal of Neural Transmission, 114(3): 367-72, 2007. PDF

C. Daniels, M. Peller, S. Wolff, K. Alfke, K. Witt, C. Gaser, O. Jansen, H.R. Siebner, G. Deuschl.
Voxel-based morphometry shows no decreases in cerebellar gray matter volume in essential tremor.
Neurology, 67(8): 1452-1456, 2006. PDF

C. Gaser, E. Luders E, P.M. Thompson, A.D. Lee, R.A. Dutton, J.A. Geaga, K.M. Hayashi, U. Bellugi, A.M. Galaburda, J.R. Korenberg, D.L. Mills, A.W. Toga, A.L. Reiss.
Increased local gyrification mapped in Williams syndrome.
Neuroimage, 33(1): 46-54, 2006. PDF

A. May, C. Gaser.
Magnetic resonance-based morphometry: a window into structural plasticity of the brain.
Current Opinion in Neurology, 19: 407-411, 2006.

K. Lasek, R. Lender, C. Gaser, J. Hagenah, U. Walter, A. Wolters, N. Kock, S. Steinlechner, M. Nagel, C. Zuhlke, M.F. Nitschke, K. Brockmann, C. Klein, A. Rolfs, F. Binkofski.
Morphological basis for the spectrum of clinical deficits in spinocerebellar ataxia 17 (SCA17).
Brain, 129: 2341-2352, 2006. PDF

A. Jatzko, S. Rothenhofer, A. Schmitt, C. Gaser, T. Demirakca, W. Weber-Fahr, M. Wessa, V. Magnotta, D.F. Braus.
Hippocampal volume in chronic posttraumatic stress disorder (PTSD): MRI study using two different evaluation methods.
Journal of Affective Disorders, 94: 121-126, 2006. PDF

T. Etgen, M. Muhlau, C. Gaser, D. Sander.
Bilateral putaminal grey-matter increase in primary blepharospasm.
Journal of Neurology, Neurosurgery & Psychiatry, 77: 1017-1020, 2006. PDF

M. Muhlau, J.P. Rauschecker, E. Oestreicher, C. Gaser, M. Rottinger, A.M. Wohlschlager, F. Simon, T. Etgen, B. Conrad, D. Sander.
Structural Brain Changes in Tinnitus.
Cerebral Cortex, 16: 1283-1288, 2006. PDF

B. Draganski, C. Gaser, G. Kempermann, H.G. Kuhn, J. Winkler, C. Buchel, A. May.
Temporal and spatial dynamics of brain structure changes during extensive learning.
Journal of Neuroscience, 26(23): 6314-7, 2006. PDF

E. Luders, P.M. Thompson, K.L. Narr, A.W. Toga, L. Jancke, C. Gaser.
A curvature-based approach to estimate local gyrification on the cortical surface.
Neuroimage, 29(4): 1224-30, 2006. PDF

N. Gaab, C. Gaser, G. Schlaug.
Improvement-related functional plasticity following pitch memory training.
Neuroimage, 31(1): 255-63, 2006. PDF

1997-2004


E. Luders, C. Gaser, L. Jäncke, G. Schlaug.
A voxel-based approach to gray matter asymmetries.
Neuroimage, 22: 656-664, 2004. PDF

B. Draganski, C. Gaser, V. Busch, G. Schuierer, U. Bogdahn, A. May.
Changes in grey matter induced by training.
Nature, 427:311-312, 2004. PDF

C. Gaser, I. Nenadic, B. Buchsbaum, E. Hazlett, M. S. Buchsbaum.
Ventricular enlargement in schizophrenia related to volume reduction of the thalamus.
American Journal of Psychiatry, 161:154-156, 2004. PDF

C. Gaser, I. Nenadic, H.-P. Volz, C. Büchel, H. Sauer.
Structural Neuroanatomy of ”Hearing Voices”: A Fronto-temporal Structural Abnormality Associated with Hallucinations in Schizophrenia.
Cerebral Cortex, 14:91-96, 2004. PDF

C. Gaser, G. Schlaug.
Gray Matter Differences between Musicians and Non-Musicians.
Annals of the New York Academy of Sciences, 999: 54-58, 2003. PDF

C. Gaser, G. Schlaug.
Brain Structures differ between Musicians and Non-Musicians.
Journal of Neuroscience, 27:9240-9245, 2003. PDF
This week in Journal of Neuroscience

N. Gaab, C. Gaser, T. Zaehle, L. Jäncke, G. Schlaug.
Functional anatomy of pitch memory-a fMRI study with sparse temporal sampling.
Neuroimage, 19:1417-1426, 2003. PDF

I. Nenadic, C. Gaser, H.-P. Volz, T. Rammsayer, H. Sauer.
Processing of temporal information and the basal ganglia: new evidence from fMRI.
Experimental Brain Research, 148:238-46, 2003. PDF

K.-J. Bär, C. Gaser, I. Nenadic, H. Sauer.
Functional anatomy of coenaesthesia: fMRI during painful somatosensory hallucinations.
Neuroreport, 13(6):805-808, May 2002.

P. Georgiewa, R. Rzanny, C. Gaser, U. J. Gerhard, U. Vieweg, D. Freesmeyer, H. J. Mentzel, W. A. Kaiser, B. Blanz.
Phonological processing in dyslexic children: a study combining functional imaging and event related potentials.
Neuroscience Letters, 318(1):5-8, January 18 2002. PDF

C. Gaser, I. Nenadic, B. Buchsbaum, E. Hazlett, M. S. Buchsbaum.
Deformation-based morphometry and its relation to conventional volumetry of brain lateral ventricles in MRI.
Neuroimage, 13:1140-1145, 2001. PDF

H.-P. Volz, I. Nenadic, C. Gaser, T. Rammsayer, H. Sauer.
Time estimation in schizophrenia: an fMRI study at adjusted levels of difficulty.
Neuroreport, 12:313-316, 2001.

C. Dettmers, T. Adler, R. Rzanny, R. van Schayk, C. Gaser, T. Weiss, W. H. Miltner, L. Brückner, C. Weiller.
Increased excitability in the primary motor cortex and supplementary motor area in patients with phantom limb pain after upper limb amputation.
Neuroscience Letters, 307:109-112, 2001. PDF

S. Riehemann, H.-P. Volz, P. Stützer, S. Smesny, C. Gaser, H. Sauer.
Hypofrontality in neuroleptic-naive schizophrenic patients during the Wisconsin Card Sorting Test – a fMRI study.
European Archives of Psychiatry and Clinical Neuroscience, 25:66-71, 2001. PDF

H.-P. Volz, C. Gaser, H. Sauer.
Supporting evidence for the model of cognitive dysmetria – a structural MRI study using deformation based morphometry.
Schizophrenia Research, 46:45-56, 2000. PDF

C. Gaser, H.-P. Volz, S. Kiebel, S. Riehemann, H. Sauer.
Detecting structural changes in whole brain based on nonlinear deformations – application to schizophrenia research.
Neuroimage, 10:107-113, 1999. PDF

H.-P. Volz, C. Gaser, F. Häger, R. Rzanny, J. Pönisch, H.-J. Mentzel, W. A. Kaiser, H. Sauer.
Decreased frontal activation in schizophrenics during stimulation with the Continuous Performance Test – a functional magnetic resonance study.
European Psychiatry, 14:17-24, 1999. PDF

H.-J. Mentzel, C. Gaser, H.-P. Volz, R. Rzanny, F. Häger, H. Sauer, W. A. Kaiser.
Cognitive stimulation by using the Wisconsin Card Sorting Test – a functional magnetic resonance imaging study at 1.5 Tesla.
Radiology, 207:399-404, 1998. PDF

F. Häger, H.-P. Volz, C. Gaser, H.-J. Mentzel, W. A. Kaiser, H. Sauer.
Challenging the anterior attentional system with a continuous performance task – a functional magnetic resonance approach.
European Archives of Psychiatry and Clinical Neuroscience, 248:161-70, 1998. PDF

H.-P. Volz, C. Gaser, F. Häger, R. Rzanny, H.-J. Mentzel, I. Kreitschmann-Andermahr, W. A. Kaiser, H. Sauer.
Brain activation during cognitive stimulation with the Wisconsin Card Sorting Test – a functional MRI study of healthy volunteers and schizophrenics.
Psychiatry Research Neuroimaging, 75:145-157, 1997. PDF

Books and bookchapters


K. Franke, C. Gaser, N. Cherbuin, J.H. Cole, eds.
Individualized Assessment of Brain Aging Across the Lifespan: Applications in Health and Disease.
In: Frontiers Media SA. doi: 10.3389/978-2-88963-902-1, 2020. PDF

R. Dahnke, C. Gaser.
Surface and Shape Analysis. In: Spalletta G., Piras F., Gili T. (eds) Brain Morphometry. Neuromethods, vol 136. Humana Press, New York, NY, pages 5-73, 2018. PDF

C. Gaser.
Structural MRI: Morphometry.
In: Neuroeconomics (edited by M. Reuter and C. Montag). Springer Verlag, pages 399-409, 2016. PDF

F. Kurth, E. Luders, C. Gaser.
Voxel-Based Morphometry.
In: Brain Mapping: An Encyclopedic Reference (edited by Arthur W. Toga). Academic Press: Elsevier, vol. 1, pages 345-349, 2015. PDF

C. Gaser.
Deformationsbasierte Morphometrie: Eine Methode zur Analyse hirnstruktureller Veränderungen.
VDM Verlag Dr. Müller, 2008.

C. Gaser.
Morphometrie.
In: Funktionelle Bildgebung in Psychiatrie und Psychotherapie (edited by H. Walter). Schattauer Verlag, Stuttgart, pages 89-104, 2005. PDF

C. Gaser.
Neue Verfahren zur Analyse von Hirnstruktur mittels Deformationsbasierter Morphometrie.
In: Langzeitverlauf und Langzeittherapie der Schizophrenie (edited by H.-J. Möller, N. Müller). Springer Verlag, Berlin, pages 117-126, 2004. PDF

H. Sauer, C. Gaser, T. Rosburg, S. Smesny, H.-P. Volz.
Psychiatrische Forschung in Jena seit 1994.
In: Universitätskolloquien zur Schizophrenie (edited by H. Hippius). Steinkopff Verlag, Darmstadt, pages 57-74, 2003.

C. Gaser.
Deformationsbasierte Morphometrie – eine Methode zur Analyse hirnstruktureller Veränderungen.
PhD Thesis, 2001. PDF

H. Sauer, C. Gaser, F. Häger, H.-P. Volz.
Das derzeit gültige Modell der Schizophrenie und Befunde zur Chronifizierung der Psychosen.
In: Langzeittherapie der Schizophrenie (edited by B. Eikelmann, M. Philipp). Springer Verlag, Berlin, pages 17-27, 2000.

Full length abstracts in series, books or proceedings


K. Franke, R. Dahnke, G. Clarke, A. Kuo, C. Li, P. Nathanielsz, M. Schwab, C. Gaser
MRI based biomarker for brain aging in rodents and non-human primates.
In: International Workshop on Pattern Recognition in Neuroimaging (PRNI) 2016, pages 1-4. Springer, 2016. PDF.

E. Moradi, J. Tohka, C. Gaser
Semi-supervised learning in MCI-to-ad conversion prediction – When is unlabeled data useful?
In: International Workshop on Pattern Recognition in Neuroimaging (PRNI) 2014, pages 1-4. Springer, 2014. PDF.

K. Franke, M. Ristow, C. Gaser
Gender-Specific Effects of Health and Lifestyle Markers on Individual BrainAGE.
In: International Workshop on Pattern Recognition in Neuroimaging (PRNI) 2013, pages 94-97. Springer, 2013. PDF.

R. Yotter, R. Dahnke, C. Gaser
Distinct pattern of brain structural deficits in sub-syndromes of schizophrenia delineated by psychopathology.
In: Proceedings of Medical Image Computing and Computer Aided Intervention (MICCAI’09), volume 5762 LNCS, pages 125-132. Springer, 2009. PDF.

C. Gaser, I. Nenadic, H. Sauer.
Analyse longitudinaler hirnstruktureller Veränderungen mit Deformationsbasierter Morphometrie.
In: Bildverarbeitung für die Medizin 2002 (edited by M. Meiler and D. Saupe and F. Kruggel and H. Handels and T. Lehmann), pages 322-325. Springer, 2002. PDF

S. Riehemann, C. Gaser, H.-P. Volz, H. Sauer.
Evaluation of cerebral 31P chemical shift images utilitizing statistical parametric mapping.
In: Medical Imaging 1999: Image Processing (edited by K. M. Hanson), volume 3661, pages 1219-1226. SPIE, 1999.

C. Gaser, S. Kiebel, S. Riehemann, H.-P. Volz, H. Sauer.
Statistical analysis of structural changes in whole brain based on nonlinear image registration.
In: Medical Imaging 1999: Image Processing (edited by K. M. Hanson), volume 3661, pages 794-801. SPIE, 1999.

C. Gaser, H.-P. Volz, S. Kiebel, H. Sauer.
Methodik und Applikation der deformationsbasierten Morphometrie.
In: Bildverarbeitung für die Medizin 1999 (edited by H. Evers and G.-P. Glombitza and T. Lehmann and H.-P. Meinzer), pages 392-397. Springer, 1999.

F. Häger, H.-P. Volz, C. Gaser, R. Rzanny, H.-J. Mentzel, W. A. Kaiser, H. Sauer.
Gender differences revealed by fMRI during the continuous performance test.
In: Quantitative and Topological EEG and MEG Analysis (edited by H. Witte, U. Zwiener, B. Schack, A. Döring), pages 180-184. Druckhaus Mayer, Jena-Erlangen, 1997.

H.-J. Mentzel, R. Rzanny, C. Gaser, F. Häger, H.-P. Volz, H. Sauer, W. A. Kaiser.
Influence of alcohol on cerebral activation during the Wisconsin Card Sorting Test – a fMRI study.
In: Quantitative and Topological EEG and MEG Analysis (edited by H. Witte, U. Zwiener, B. Schack, A. Döring), pages 178-179. Druckhaus Mayer, Jena-Erlangen, 1997.

H.-P. Volz, C. Gaser, F. Häger, R. Rzanny, H.-J. Mentzel, W. A. Kaiser, H. Sauer.
Right Frontal Activation by the Wisconsin Card Sorting Test Measured via Functional MRI.
In: Quantitative and Topological EEG and MEG Analysis (edited by H. Witte, U. Zwiener, B. Schack, A. Döring), pages 166-168. Druckhaus Mayer, Jena-Erlangen, 1997.

C. Gaser, H.-P. Volz, F. Häger, R. Rzanny, H.-J. Mentzel, W. A. Kaiser, H. Sauer.
Detection of Artifacts in analysis of Functional MRI data using 2-dimensional histograms.
In: Quantitative and Topological EEG and MEG Analysis (edited by H. Witte, U. Zwiener, B. Schack, A. Döring), pages 84-88. Druckhaus Mayer, Jena-Erlangen, 1997.